Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids

Mammary organoid growth from single primary human cells rely on distinct morphogenetic processes. Here, the authors observe by live cell imaging the importance of the plastic mechanical response of the extracellular matrix and cell migration for the underlying arborized structure formation process.

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Autores principales:	B. Buchmann, L. K. Engelbrecht, P. Fernandez, F. P. Hutterer, M. K. Raich, C. H. Scheel, A. R. Bausch
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ca6fd98434244dba96daeb649f0b2389
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spelling	oai:doaj.org-article:ca6fd98434244dba96daeb649f0b23892021-12-02T15:54:58ZMechanical plasticity of collagen directs branch elongation in human mammary gland organoids10.1038/s41467-021-22988-22041-1723https://doaj.org/article/ca6fd98434244dba96daeb649f0b23892021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22988-2https://doaj.org/toc/2041-1723Mammary organoid growth from single primary human cells rely on distinct morphogenetic processes. Here, the authors observe by live cell imaging the importance of the plastic mechanical response of the extracellular matrix and cell migration for the underlying arborized structure formation process.B. BuchmannL. K. EngelbrechtP. FernandezF. P. HuttererM. K. RaichC. H. ScheelA. R. BauschNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q B. Buchmann L. K. Engelbrecht P. Fernandez F. P. Hutterer M. K. Raich C. H. Scheel A. R. Bausch Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
description	Mammary organoid growth from single primary human cells rely on distinct morphogenetic processes. Here, the authors observe by live cell imaging the importance of the plastic mechanical response of the extracellular matrix and cell migration for the underlying arborized structure formation process.
format	article
author	B. Buchmann L. K. Engelbrecht P. Fernandez F. P. Hutterer M. K. Raich C. H. Scheel A. R. Bausch
author_facet	B. Buchmann L. K. Engelbrecht P. Fernandez F. P. Hutterer M. K. Raich C. H. Scheel A. R. Bausch
author_sort	B. Buchmann
title	Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
title_short	Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
title_full	Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
title_fullStr	Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
title_full_unstemmed	Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
title_sort	mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ca6fd98434244dba96daeb649f0b2389
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Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids

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