Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP

Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP

Abstract Background Aging and neurodegenerative diseases are typical metabolic-related processes. As a metabolism-related long non-coding RNA, EPB41L4A-AS has been reported to be potentially involved in the development of brain aging and neurodegenerative diseases. In this study, we sought to reveal...

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Bibliographic Details
Main Authors: Tingpeng Yang, Yanzhi Wang, Weijie Liao, Shikuan Zhang, Songmao Wang, Naihan Xu, Weidong Xie, Cheng Luo, Yangyang Wang, Ziqiang Wang, Yaou Zhang
Format: article
Language:EN
Published: BMC 2021
Subjects:
Aging
Neurodegenerative diseases
EPB41L4A- AS1
NAD+
ATP
H3K27Ac
Biotechnology
TP248.13-248.65
Biology (General)
QH301-705.5
Biochemistry
QD415-436
Online Access:https://doaj.org/article/caaac27d0d3f4084bc0bf300daa4794e
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https://doaj.org/article/caaac27d0d3f4084bc0bf300daa4794e

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