Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex
It is known that descending facilitation of spinal responses may contribute to chronic pain, however many studies have focussed on brainstem mechanisms. Here the authors show that stimulation of the anterior cingulate cortex increases excitatory transmission in the dorsal horn, and that this may be...
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Nature Portfolio
2018
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oai:doaj.org-article:cab2f802a1c14b699c2a653bbdddee932021-12-02T17:32:15ZTop-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex10.1038/s41467-018-04309-22041-1723https://doaj.org/article/cab2f802a1c14b699c2a653bbdddee932018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04309-2https://doaj.org/toc/2041-1723It is known that descending facilitation of spinal responses may contribute to chronic pain, however many studies have focussed on brainstem mechanisms. Here the authors show that stimulation of the anterior cingulate cortex increases excitatory transmission in the dorsal horn, and that this may be via a direct pathway independent of the brainstem.Tao ChenWataru TaniguchiQi-Yu ChenHidetoshi Tozaki-SaitohQian SongRen-Hao LiuKohei KogaTsuyoshi MatsudaYae Kaito-SugimuraJian WangZhi-Hua LiYa-Cheng LuKazuhide InoueMakoto TsudaYun-Qing LiTerumasa NakatsukaMin ZhuoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018) |
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DOAJ |
| language |
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Science Q Tao Chen Wataru Taniguchi Qi-Yu Chen Hidetoshi Tozaki-Saitoh Qian Song Ren-Hao Liu Kohei Koga Tsuyoshi Matsuda Yae Kaito-Sugimura Jian Wang Zhi-Hua Li Ya-Cheng Lu Kazuhide Inoue Makoto Tsuda Yun-Qing Li Terumasa Nakatsuka Min Zhuo Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| description |
It is known that descending facilitation of spinal responses may contribute to chronic pain, however many studies have focussed on brainstem mechanisms. Here the authors show that stimulation of the anterior cingulate cortex increases excitatory transmission in the dorsal horn, and that this may be via a direct pathway independent of the brainstem. |
| format |
article |
| author |
Tao Chen Wataru Taniguchi Qi-Yu Chen Hidetoshi Tozaki-Saitoh Qian Song Ren-Hao Liu Kohei Koga Tsuyoshi Matsuda Yae Kaito-Sugimura Jian Wang Zhi-Hua Li Ya-Cheng Lu Kazuhide Inoue Makoto Tsuda Yun-Qing Li Terumasa Nakatsuka Min Zhuo |
| author_facet |
Tao Chen Wataru Taniguchi Qi-Yu Chen Hidetoshi Tozaki-Saitoh Qian Song Ren-Hao Liu Kohei Koga Tsuyoshi Matsuda Yae Kaito-Sugimura Jian Wang Zhi-Hua Li Ya-Cheng Lu Kazuhide Inoue Makoto Tsuda Yun-Qing Li Terumasa Nakatsuka Min Zhuo |
| author_sort |
Tao Chen |
| title |
Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| title_short |
Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| title_full |
Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| title_fullStr |
Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| title_full_unstemmed |
Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| title_sort |
top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/cab2f802a1c14b699c2a653bbdddee93 |
| work_keys_str_mv |
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