Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability

Abstract The renal proximal tubule is responsible for re-absorption of the majority of the glomerular filtrate and its proper function is necessary for whole-body homeostasis. Aging, certain diseases and chemical-induced toxicity are factors that contribute to proximal tubule injury and chronic kidn...

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Auteurs principaux: Vidya Chandrasekaran, Giada Carta, Daniel da Costa Pereira, Rajinder Gupta, Cormac Murphy, Elisabeth Feifel, Georg Kern, Judith Lechner, Anna Lina Cavallo, Shailesh Gupta, Florian Caiment, Jos C. S. Kleinjans, Gerhard Gstraunthaler, Paul Jennings, Anja Wilmes
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Q
Accès en ligne:https://doaj.org/article/cabcf3e0db84468c83c49d606b6f2e22
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