Optimizing mitochondrial maintenance in extended neuronal projections.

Neurons rely on localized mitochondria to fulfill spatially heterogeneous metabolic demands. Mitochondrial aging occurs on timescales shorter than the neuronal lifespan, necessitating transport of fresh material from the soma. Maintaining an optimal distribution of healthy mitochondria requires an i...

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Bibliographic Details
Main Authors: Anamika Agrawal, Elena F Koslover
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Online Access:https://doaj.org/article/caff8740e8fa484cb5bbe12f3ad495a6
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