RIF1 promotes replication fork protection and efficient restart to maintain genome stability

Replication fork degradation can result in genome instability. Here authors reveal a role for Rif1 protein in protecting stalled replication forks from undergoing extensive, DNA2-dependent, degradation.

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Autores principales:	Chirantani Mukherjee, Vivek Tripathi, Eleni Maria Manolika, Anne Margriet Heijink, Giulia Ricci, Sarra Merzouk, H. Rudolf de Boer, Jeroen Demmers, Marcel A. T. M. van Vugt, Arnab Ray Chaudhuri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cb070f743a7d4af79f8d12d89e2dfee4
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spelling	oai:doaj.org-article:cb070f743a7d4af79f8d12d89e2dfee42021-12-02T17:33:10ZRIF1 promotes replication fork protection and efficient restart to maintain genome stability10.1038/s41467-019-11246-12041-1723https://doaj.org/article/cb070f743a7d4af79f8d12d89e2dfee42019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11246-1https://doaj.org/toc/2041-1723Replication fork degradation can result in genome instability. Here authors reveal a role for Rif1 protein in protecting stalled replication forks from undergoing extensive, DNA2-dependent, degradation.Chirantani MukherjeeVivek TripathiEleni Maria ManolikaAnne Margriet HeijinkGiulia RicciSarra MerzoukH. Rudolf de BoerJeroen DemmersMarcel A. T. M. van VugtArnab Ray ChaudhuriNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chirantani Mukherjee Vivek Tripathi Eleni Maria Manolika Anne Margriet Heijink Giulia Ricci Sarra Merzouk H. Rudolf de Boer Jeroen Demmers Marcel A. T. M. van Vugt Arnab Ray Chaudhuri RIF1 promotes replication fork protection and efficient restart to maintain genome stability
description	Replication fork degradation can result in genome instability. Here authors reveal a role for Rif1 protein in protecting stalled replication forks from undergoing extensive, DNA2-dependent, degradation.
format	article
author	Chirantani Mukherjee Vivek Tripathi Eleni Maria Manolika Anne Margriet Heijink Giulia Ricci Sarra Merzouk H. Rudolf de Boer Jeroen Demmers Marcel A. T. M. van Vugt Arnab Ray Chaudhuri
author_facet	Chirantani Mukherjee Vivek Tripathi Eleni Maria Manolika Anne Margriet Heijink Giulia Ricci Sarra Merzouk H. Rudolf de Boer Jeroen Demmers Marcel A. T. M. van Vugt Arnab Ray Chaudhuri
author_sort	Chirantani Mukherjee
title	RIF1 promotes replication fork protection and efficient restart to maintain genome stability
title_short	RIF1 promotes replication fork protection and efficient restart to maintain genome stability
title_full	RIF1 promotes replication fork protection and efficient restart to maintain genome stability
title_fullStr	RIF1 promotes replication fork protection and efficient restart to maintain genome stability
title_full_unstemmed	RIF1 promotes replication fork protection and efficient restart to maintain genome stability
title_sort	rif1 promotes replication fork protection and efficient restart to maintain genome stability
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/cb070f743a7d4af79f8d12d89e2dfee4
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RIF1 promotes replication fork protection and efficient restart to maintain genome stability

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