Correlative scanning-transmission electron microscopy reveals that a chimeric flavivirus is released as individual particles in secretory vesicles.

The intracellular morphogenesis of flaviviruses has been well described, but flavivirus release from the host cell remains poorly documented. We took advantage of the optimized production of an attenuated chimeric yellow fever/dengue virus for vaccine purposes to study this phenomenon by microscopic...

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Auteurs principaux: Julien Burlaud-Gaillard, Caroline Sellin, Sonia Georgeault, Rustem Uzbekov, Claude Lebos, Jean-Marc Guillaume, Philippe Roingeard
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/cb212d60407f476fb56464201793e939
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