FGF23/FGFR4-mediated left ventricular hypertrophy is reversible

FGF23/FGFR4-mediated left ventricular hypertrophy is reversible

Abstract Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. Serum FGF23 levels are highly elevated in patients...

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Autores principales: Alexander Grabner, Karla Schramm, Neerupma Silswal, Matt Hendrix, Christopher Yanucil, Brian Czaya, Saurav Singh, Myles Wolf, Sven Hermann, Jörg Stypmann, Giovana Seno Di Marco, Marcus Brand, Michael J. Wacker, Christian Faul
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/cb4d0dfc6664400eb70380aa34adcde3
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https://doaj.org/article/cb4d0dfc6664400eb70380aa34adcde3

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