Mass & secondary structure propensity of amino acids explain their mutability and evolutionary replacements

Abstract Why is an amino acid replacement in a protein accepted during evolution? The answer given by bioinformatics relies on the frequency of change of each amino acid by another one and the propensity of each to remain unchanged. We propose that these replacement rules are recoverable from the se...

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Autores principales: Hugo J. Bohórquez, Carlos F. Suárez, Manuel E. Patarroyo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cb76b1d6138444888f1136d1f6f0f2f2
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