In vitro synthesis of gene-length single-stranded DNA
Abstract Single-stranded DNA (ssDNA) increases the likelihood of homology directed repair with reduced cellular toxicity. However, ssDNA synthesis strategies are limited by the maximum length attainable, ranging from a few hundred nucleotides for chemical synthesis to a few thousand nucleotides for...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/cb86edf54d00480d9e19c68973dc90bb |
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