Lowered fasting chenodeoxycholic acid correlated with the decrease of fibroblast growth factor 19 in Chinese subjects with impaired fasting glucose

Abstract The gut-derived hormone Fibroblast growth factor 19 (FGF19) could regulate glucose metabolism and is induced by bile acids (BAs) through activating Farnesoid X Receptor (FXR). FGF19 was found to decrease in subjects with isolated-impaired fasting glucose (I-IFG) and type 2 diabetes mellitus...

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Auteurs principaux: Jing Zhang, Huating Li, Hu Zhou, Li Fang, Jingjing Xu, Han Yan, Shuqin Chen, Qianqian Song, Yinan Zhang, Aimin Xu, Qichen Fang, Yang Ye, Weiping Jia
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/cb967b52d64844b2ac9446375ae654b7
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