Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs

RNA G-quadruplexes (RG4) occur in vivo and have regulatory roles in mRNA metabolism. Here the authors show that the guanine residue stretches at the 5’ end of tRNA-derived stress-induced RNAs mediate the formation of tetramolecular RG4 structures, which play a role in the post-transcriptional regula...

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Autores principales: Shawn M. Lyons, Dorota Gudanis, Steven M. Coyne, Zofia Gdaniec, Pavel Ivanov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cba8c36886fd443aa55acf7c6f648780
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