The architecture and stabilisation of flagellotropic tailed bacteriophages

Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.

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Autores principales: Joshua M. Hardy, Rhys A. Dunstan, Rhys Grinter, Matthew J. Belousoff, Jiawei Wang, Derek Pickard, Hariprasad Venugopal, Gordon Dougan, Trevor Lithgow, Fasséli Coulibaly
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/cbbfd27156b94771800d0722f02aa153
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Sumario:Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.