The architecture and stabilisation of flagellotropic tailed bacteriophages
Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.
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Nature Portfolio
2020
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oai:doaj.org-article:cbbfd27156b94771800d0722f02aa1532021-12-02T18:47:08ZThe architecture and stabilisation of flagellotropic tailed bacteriophages10.1038/s41467-020-17505-w2041-1723https://doaj.org/article/cbbfd27156b94771800d0722f02aa1532020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17505-whttps://doaj.org/toc/2041-1723Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.Joshua M. HardyRhys A. DunstanRhys GrinterMatthew J. BelousoffJiawei WangDerek PickardHariprasad VenugopalGordon DouganTrevor LithgowFasséli CoulibalyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q |
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Science Q Joshua M. Hardy Rhys A. Dunstan Rhys Grinter Matthew J. Belousoff Jiawei Wang Derek Pickard Hariprasad Venugopal Gordon Dougan Trevor Lithgow Fasséli Coulibaly The architecture and stabilisation of flagellotropic tailed bacteriophages |
description |
Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses. |
format |
article |
author |
Joshua M. Hardy Rhys A. Dunstan Rhys Grinter Matthew J. Belousoff Jiawei Wang Derek Pickard Hariprasad Venugopal Gordon Dougan Trevor Lithgow Fasséli Coulibaly |
author_facet |
Joshua M. Hardy Rhys A. Dunstan Rhys Grinter Matthew J. Belousoff Jiawei Wang Derek Pickard Hariprasad Venugopal Gordon Dougan Trevor Lithgow Fasséli Coulibaly |
author_sort |
Joshua M. Hardy |
title |
The architecture and stabilisation of flagellotropic tailed bacteriophages |
title_short |
The architecture and stabilisation of flagellotropic tailed bacteriophages |
title_full |
The architecture and stabilisation of flagellotropic tailed bacteriophages |
title_fullStr |
The architecture and stabilisation of flagellotropic tailed bacteriophages |
title_full_unstemmed |
The architecture and stabilisation of flagellotropic tailed bacteriophages |
title_sort |
architecture and stabilisation of flagellotropic tailed bacteriophages |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/cbbfd27156b94771800d0722f02aa153 |
work_keys_str_mv |
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