The architecture and stabilisation of flagellotropic tailed bacteriophages

Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.

Guardado en:
Detalles Bibliográficos
Autores principales: Joshua M. Hardy, Rhys A. Dunstan, Rhys Grinter, Matthew J. Belousoff, Jiawei Wang, Derek Pickard, Hariprasad Venugopal, Gordon Dougan, Trevor Lithgow, Fasséli Coulibaly
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/cbbfd27156b94771800d0722f02aa153
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:cbbfd27156b94771800d0722f02aa153
record_format dspace
spelling oai:doaj.org-article:cbbfd27156b94771800d0722f02aa1532021-12-02T18:47:08ZThe architecture and stabilisation of flagellotropic tailed bacteriophages10.1038/s41467-020-17505-w2041-1723https://doaj.org/article/cbbfd27156b94771800d0722f02aa1532020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17505-whttps://doaj.org/toc/2041-1723Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.Joshua M. HardyRhys A. DunstanRhys GrinterMatthew J. BelousoffJiawei WangDerek PickardHariprasad VenugopalGordon DouganTrevor LithgowFasséli CoulibalyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joshua M. Hardy
Rhys A. Dunstan
Rhys Grinter
Matthew J. Belousoff
Jiawei Wang
Derek Pickard
Hariprasad Venugopal
Gordon Dougan
Trevor Lithgow
Fasséli Coulibaly
The architecture and stabilisation of flagellotropic tailed bacteriophages
description Flagellotropic phages spin down flagella to reach the bacterial surface and must withstand remarkable drag forces. Here authors show how two nested sets of chainmail stabilise the viral head and a beta-hairpin regulates the formation of the robust yet pliable tail, characteristic of siphoviruses.
format article
author Joshua M. Hardy
Rhys A. Dunstan
Rhys Grinter
Matthew J. Belousoff
Jiawei Wang
Derek Pickard
Hariprasad Venugopal
Gordon Dougan
Trevor Lithgow
Fasséli Coulibaly
author_facet Joshua M. Hardy
Rhys A. Dunstan
Rhys Grinter
Matthew J. Belousoff
Jiawei Wang
Derek Pickard
Hariprasad Venugopal
Gordon Dougan
Trevor Lithgow
Fasséli Coulibaly
author_sort Joshua M. Hardy
title The architecture and stabilisation of flagellotropic tailed bacteriophages
title_short The architecture and stabilisation of flagellotropic tailed bacteriophages
title_full The architecture and stabilisation of flagellotropic tailed bacteriophages
title_fullStr The architecture and stabilisation of flagellotropic tailed bacteriophages
title_full_unstemmed The architecture and stabilisation of flagellotropic tailed bacteriophages
title_sort architecture and stabilisation of flagellotropic tailed bacteriophages
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/cbbfd27156b94771800d0722f02aa153
work_keys_str_mv AT joshuamhardy thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT rhysadunstan thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT rhysgrinter thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT matthewjbelousoff thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT jiaweiwang thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT derekpickard thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT hariprasadvenugopal thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT gordondougan thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT trevorlithgow thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT fasselicoulibaly thearchitectureandstabilisationofflagellotropictailedbacteriophages
AT joshuamhardy architectureandstabilisationofflagellotropictailedbacteriophages
AT rhysadunstan architectureandstabilisationofflagellotropictailedbacteriophages
AT rhysgrinter architectureandstabilisationofflagellotropictailedbacteriophages
AT matthewjbelousoff architectureandstabilisationofflagellotropictailedbacteriophages
AT jiaweiwang architectureandstabilisationofflagellotropictailedbacteriophages
AT derekpickard architectureandstabilisationofflagellotropictailedbacteriophages
AT hariprasadvenugopal architectureandstabilisationofflagellotropictailedbacteriophages
AT gordondougan architectureandstabilisationofflagellotropictailedbacteriophages
AT trevorlithgow architectureandstabilisationofflagellotropictailedbacteriophages
AT fasselicoulibaly architectureandstabilisationofflagellotropictailedbacteriophages
_version_ 1718377650595037184