Design of a Quantitative LC-MS Method for Residual Toxins Adenylate Cyclase Toxin (ACT), Dermonecrotic Toxin (DNT) and Tracheal Cytotoxin (TCT) in <em>Bordetella pertussis</em> Vaccines

The antigens for acellular pertussis vaccines are made up of protein components that are purified directly from <i>Bordetella pertussis (B. pertussis)</i> bacterial fermentation. As such, there are additional <i>B. pertussis</i> toxins that must be monitored as residuals duri...

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Autores principales: Lisa Szymkowicz, Jeffery Gerard, Benjamin Messham, Wai Wan Vivian Tam, D. Andrew James
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/cc2c323c6ae141afa35d9bbd31203796
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