<i>Sulfatase</i>-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway

Transforming growth factor-β (TGF-β) activates hepatic stellate cells (HSCs), which drive liver fibrosis via the production and deposition of extracellular matrix (ECM). We aimed to elucidate the mechanistic role of <i>sulfatase</i>-2 (SULF2) in liver fibrosis. To this end, we induced li...

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Autores principales: Ikuo Nakamura, Faizal Z. Asumda, Catherine D. Moser, Yoo Na N. Kang, Jin-Ping Lai, Lewis R. Roberts
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/cc40c55beceb4fb8940093a3f1e36b86
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