<i>Sulfatase</i>-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway
Transforming growth factor-β (TGF-β) activates hepatic stellate cells (HSCs), which drive liver fibrosis via the production and deposition of extracellular matrix (ECM). We aimed to elucidate the mechanistic role of <i>sulfatase</i>-2 (SULF2) in liver fibrosis. To this end, we induced li...
Guardado en:
Autores principales: | Ikuo Nakamura, Faizal Z. Asumda, Catherine D. Moser, Yoo Na N. Kang, Jin-Ping Lai, Lewis R. Roberts |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/cc40c55beceb4fb8940093a3f1e36b86 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Obesidad: factor de riesgo para esteatohepatitis y fibrosis hepática
por: Poniachik T,Jaime, et al.
Publicado: (2002) -
Blancos terapéuticos potenciales para revertir la cirrosis hepática
por: García B,Leonel, et al.
Publicado: (2007) -
p70 Ribosomal Protein S6 Kinase Is a Checkpoint of Human Hepatic Stellate Cell Activation and Liver Fibrosis in MiceSummary
por: Florian P. Reiter, et al.
Publicado: (2022) -
Identifying High-Risk NASH Patients: What We Know so Far
por: Schulz M, et al.
Publicado: (2020) -
Truncated Milk Fat Globule-EGF-like Factor 8 Ameliorates Liver Fibrosis via Inhibition of Integrin-TGFβ Receptor Interaction
por: Geun Ho An, et al.
Publicado: (2021)