A tumor-penetrable drug nanococktail made from human histones for interventional nucleus-targeted chemophotothermal therapy of drug-resistant tumors

A tumor-penetrable drug nanococktail made from human histones for interventional nucleus-targeted chemophotothermal therapy of drug-resistant tumors

Nanoparticle-based chemophotothermal therapy (CPT) is a promising treatment for multidrug resistant tumors. In this study, a drug nanococktail of DIR825@histone was developed by employing doxorubicin (DOX), NIR dye IR825 and human histones for interventional nucleus-targeted CPT of multidrug resista...

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Bibliographic Details
Main Authors: Jianquan Guo, Dongsheng Tan, Chenmei Lou, Shiying Guo, Xing Jin, Haijing Qu, Lijia Jing, Sijin Li
Format: article
Language:EN
Published: KeAi Communications Co., Ltd. 2022
Subjects:
Human histones
Chemotherapy
Photothermal therapy
Nuclear targeting
Localized intervention
Drug resistant tumor
Materials of engineering and construction. Mechanics of materials
TA401-492
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/cc4b0abac14d4b2c8edd406d42ac2b03
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https://doaj.org/article/cc4b0abac14d4b2c8edd406d42ac2b03

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