Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses
Asymmetric subcellular mRNA distribution is important for local translation of neuronal mRNAs. Here the authors employed MS2 live-cell imaging and showed that the reporter mRNA containing the 3’ UTR of Rgs4 shows an anterograde transport bias, dependent on neuronal activity and the protein Staufen2,...
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Main Authors: | Karl E. Bauer, Inmaculada Segura, Imre Gaspar, Volker Scheuss, Christin Illig, Georg Ammer, Saskia Hutten, Eugénia Basyuk, Sandra M. Fernández-Moya, Janina Ehses, Edouard Bertrand, Michael A. Kiebler |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/cc4d41928ef64ea9ba34f9e96c74913b |
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