Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis

Abstract Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. How...

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Autores principales: Xiaofang Cui, Linmo Chang, Youwei Li, Qianrui Lv, Fei Wang, Yaxian Lin, Weiyang Li, Jonathan D. Meade, Jamie C. Walden, Peng Liang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/cc6ab514259e46329891bf7dc1a71817
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