MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
Deregulated MYC activity is oncogenic and is deregulated in a large fraction of human cancers. Here the authors find that protein phosphatase 1 and its regulatory subunit PNUTS controls MYC stability and its interaction with chromatin.
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| Main Authors: | , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/cc8066c5d0d249efbc4b69b3a8efd7c8 |
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