Changes on proteomic and metabolomic profile in serum of mice induced by chronic exposure to tramadol

Abstract Tramadol is an opioid used as an analgesic for treating moderate or severe pain. The long-term use of tramadol can induce several adverse effects. The toxicological mechanism of tramadol abuse is unclear. Limited literature available indicates the change of proteomic profile after chronic e...

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Autores principales: Shukun Jiang, Guojie Liu, Huiya Yuan, Enyu Xu, Wei Xia, Xiaoyu Zhang, Junting Liu, Lina Gao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cc95a248587f46d2af5358b00d95bcc3
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