Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis.

Suppressor of cytokine signalling 3 (SOCS3) negatively regulates STAT3 activation in response to several cytokines such as those in the gp130-containing IL-6 receptor family. Thus, SOCS3 may play a major role in immune responses to pathogens. In the present study, the role of SOCS3 in M. tuberculosi...

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Détails bibliographiques
Auteurs principaux: Berit Carow, Ann-Kathrin Reuschl, Dolores Gavier-Widén, Brendan J Jenkins, Matthias Ernst, Akihiko Yoshimura, Benedict J Chambers, Martin E Rottenberg
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/ccb20071a27346fea8f7fc0ef60e5438
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