Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis.
Suppressor of cytokine signalling 3 (SOCS3) negatively regulates STAT3 activation in response to several cytokines such as those in the gp130-containing IL-6 receptor family. Thus, SOCS3 may play a major role in immune responses to pathogens. In the present study, the role of SOCS3 in M. tuberculosi...
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Auteurs principaux: | Berit Carow, Ann-Kathrin Reuschl, Dolores Gavier-Widén, Brendan J Jenkins, Matthias Ernst, Akihiko Yoshimura, Benedict J Chambers, Martin E Rottenberg |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Sujets: | |
Accès en ligne: | https://doaj.org/article/ccb20071a27346fea8f7fc0ef60e5438 |
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