Determinants of GPI-PLC localisation to the flagellum and access to GPI-anchored substrates in trypanosomes.
In Trypanosoma brucei, glycosylphosphatidylinositol phospholipase C (GPI-PLC) is a virulence factor that releases variant surface glycoprotein (VSG) from dying cells. In live cells, GPI-PLC is localised to the plasma membrane where it is concentrated on the flagellar membrane, so activity or access...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2013
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| Accès en ligne: | https://doaj.org/article/ccc5b0e136ed4a80bba99f5602398c83 |
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