A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors.
The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, signi...
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Main Authors: | Shawn Stapleton, Michael Milosevic, Christine Allen, Jinzi Zheng, Michael Dunne, Ivan Yeung, David A Jaffray |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Subjects: | |
Online Access: | https://doaj.org/article/ccdf03f2a6c44b06a1ed145eed2b6e84 |
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