ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7

Emerging SARS-CoV-2 variants raise concerns about vaccine effectiveness. Here, the authors show that the ChAdOx1 nCoV-19 (AZD1222) vaccine protects Syrian hamsters from pulmonary infection and disease after infection with SARS-CoV-2 B.1.351 or B.1.1.7 variants.

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Autores principales: Robert J. Fischer, Neeltje van Doremalen, Danielle R. Adney, Claude Kwe Yinda, Julia R. Port, Myndi G. Holbrook, Jonathan E. Schulz, Brandi N. Williamson, Tina Thomas, Kent Barbian, Sarah L. Anzick, Stacy Ricklefs, Brian J. Smith, Dan Long, Craig Martens, Greg Saturday, Emmie de Wit, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cd521c32186f4059b6298768dcc0d51a
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spelling oai:doaj.org-article:cd521c32186f4059b6298768dcc0d51a2021-12-02T18:37:28ZChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.710.1038/s41467-021-26178-y2041-1723https://doaj.org/article/cd521c32186f4059b6298768dcc0d51a2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26178-yhttps://doaj.org/toc/2041-1723Emerging SARS-CoV-2 variants raise concerns about vaccine effectiveness. Here, the authors show that the ChAdOx1 nCoV-19 (AZD1222) vaccine protects Syrian hamsters from pulmonary infection and disease after infection with SARS-CoV-2 B.1.351 or B.1.1.7 variants.Robert J. FischerNeeltje van DoremalenDanielle R. AdneyClaude Kwe YindaJulia R. PortMyndi G. HolbrookJonathan E. SchulzBrandi N. WilliamsonTina ThomasKent BarbianSarah L. AnzickStacy RicklefsBrian J. SmithDan LongCraig MartensGreg SaturdayEmmie de WitSarah C. GilbertTeresa LambeVincent J. MunsterNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Robert J. Fischer
Neeltje van Doremalen
Danielle R. Adney
Claude Kwe Yinda
Julia R. Port
Myndi G. Holbrook
Jonathan E. Schulz
Brandi N. Williamson
Tina Thomas
Kent Barbian
Sarah L. Anzick
Stacy Ricklefs
Brian J. Smith
Dan Long
Craig Martens
Greg Saturday
Emmie de Wit
Sarah C. Gilbert
Teresa Lambe
Vincent J. Munster
ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
description Emerging SARS-CoV-2 variants raise concerns about vaccine effectiveness. Here, the authors show that the ChAdOx1 nCoV-19 (AZD1222) vaccine protects Syrian hamsters from pulmonary infection and disease after infection with SARS-CoV-2 B.1.351 or B.1.1.7 variants.
format article
author Robert J. Fischer
Neeltje van Doremalen
Danielle R. Adney
Claude Kwe Yinda
Julia R. Port
Myndi G. Holbrook
Jonathan E. Schulz
Brandi N. Williamson
Tina Thomas
Kent Barbian
Sarah L. Anzick
Stacy Ricklefs
Brian J. Smith
Dan Long
Craig Martens
Greg Saturday
Emmie de Wit
Sarah C. Gilbert
Teresa Lambe
Vincent J. Munster
author_facet Robert J. Fischer
Neeltje van Doremalen
Danielle R. Adney
Claude Kwe Yinda
Julia R. Port
Myndi G. Holbrook
Jonathan E. Schulz
Brandi N. Williamson
Tina Thomas
Kent Barbian
Sarah L. Anzick
Stacy Ricklefs
Brian J. Smith
Dan Long
Craig Martens
Greg Saturday
Emmie de Wit
Sarah C. Gilbert
Teresa Lambe
Vincent J. Munster
author_sort Robert J. Fischer
title ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
title_short ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
title_full ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
title_fullStr ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
title_full_unstemmed ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
title_sort chadox1 ncov-19 (azd1222) protects syrian hamsters against sars-cov-2 b.1.351 and b.1.1.7
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/cd521c32186f4059b6298768dcc0d51a
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