Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes

Anteroposterior axis extension during gastrulation is dynamically coordinated, but how this is regulated at a molecular level is unclear. Here, the authors show in zebrafish that the chromatin factor Gon4l, encoded by ugly duckling, coordinates axis extension by modulating EpCAM and Integrinα3b expr...

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Bibliographic Details
Main Authors: Margot L. K. Williams, Atsushi Sawada, Terin Budine, Chunyue Yin, Paul Gontarz, Lilianna Solnica-Krezel
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/cd8d2c162cea4451acb9c892aace8007
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