ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA.

ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA.

<h4>Background</h4>Neurons extend their dendrites and axons to build functional neural circuits, which are regulated by both positive and negative signals during development. Brain-derived neurotrophic factor (BDNF) is a positive regulator for neurite outgrowth and neuronal survival but...

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Main Authors: Ying Sun, Yoon Lim, Fang Li, Shen Liu, Jian-Jun Lu, Rainer Haberberger, Jin-Hua Zhong, Xin-Fu Zhou
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/cd9dec0a8aab4630a877a6bb7e6fcd97
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