ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA.
<h4>Background</h4>Neurons extend their dendrites and axons to build functional neural circuits, which are regulated by both positive and negative signals during development. Brain-derived neurotrophic factor (BDNF) is a positive regulator for neurite outgrowth and neuronal survival but...
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/cd9dec0a8aab4630a877a6bb7e6fcd97 |
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