Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients

Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients

This study aimed to systematically investigate trans-eQTLs of CYP3A4 and CYP3A5 affecting tacrolimus trough blood concentrations in Chinese renal transplant patients. We used Plink v1.90 to perform data quality control and linear regression analysis on GTEx v8 data. SNPs with p-value < 0.05 were...

Full description

Saved in:
Bibliographic Details
Main Authors: Huijie Lu, Haixia Jiang, Siyao Yang, Chengcheng Li, Chuanjiang Li, Ruifan Shao, Pai Zhang, Daoyi Wang, Zhiwei Liu, Huana Qi, Yinuan Cai, Wenbin Xu, Xiaojie Bao, Hailan Wang, Liang Li
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
CYP3A5
CYP3A4
Tacrolimus
Trans-eQTL
GTEx
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/cdbe852b1c434da889ba57205a394fe6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/cdbe852b1c434da889ba57205a394fe6

Similar Items