A systematic proteomic study of irradiated DNA repair deficient Nbn-mice.

<h4>Background</h4>The NBN gene codes for the protein nibrin, which is involved in the detection and repair of DNA double strand breaks (DSBs). The NBN gene is essential in mammals.<h4>Methodology/principal findings</h4>We have used a conditional null mutant mouse model in a...

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Autores principales: Anna Melchers, Lars Stöckl, Janina Radszewski, Marco Anders, Harald Krenzlin, Candy Kalischke, Regina Scholz, Andreas Jordan, Grit Nebrich, Joachim Klose, Karl Sperling, Martin Digweed, Ilja Demuth
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/cdf537450a1d4aebbc16ca29599ebf77
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