Computational design of single-stranded DNA hairpin aptamers immobilized on a biosensor substrate

Abstract Aptamer interactions with a surface of attachment are central to the design and performance of aptamer-based biosensors. We have developed a computational modeling approach to study different system designs—including different aptamer-attachment ends, aptamer surface densities, aptamer orie...

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Autores principales: Iman Jeddi, Leonor Saiz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cdf59dc121e4481ab88b7ff2f44f5cd2
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