Computational design of single-stranded DNA hairpin aptamers immobilized on a biosensor substrate
Abstract Aptamer interactions with a surface of attachment are central to the design and performance of aptamer-based biosensors. We have developed a computational modeling approach to study different system designs—including different aptamer-attachment ends, aptamer surface densities, aptamer orie...
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/cdf59dc121e4481ab88b7ff2f44f5cd2 |
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