Telomere length shows no association with BRCA1 and BRCA2 mutation status.

This study aimed to determine whether telomere length (TL) is a marker of cancer risk or genetic status amongst two cohorts of BRCA1 and BRCA2 mutation carriers and controls. The first group was a prospective set of 665 male BRCA1/2 mutation carriers and controls (mean age 53 years), all healthy at...

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Auteurs principaux: Emma Killick, Malgorzata Tymrakiewicz, Clara Cieza-Borrella, Paula Smith, Deborah J Thompson, Karen A Pooley, Doug F Easton, Elizabeth Bancroft, Elizabeth Page, Daniel Leongamornlert, IMPACT collaborators, Zsofia Kote-Jarai, Rosalind A Eeles
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/cdfabafadb5b476489a69b8ed1a6df47
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