Structural modularity of the XIST ribonucleoprotein complex

The long noncoding RNA XIST plays a central role in sex-specific gene expression in humans by silencing one of two X chromosomes in female cells. Here the authors show that higher order secondary structure creates the modular domain structure of XIST ribonucleoprotein complex and spatial separation...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhipeng Lu, Jimmy K. Guo, Yuning Wei, Diana R. Dou, Brian Zarnegar, Qing Ma, Rui Li, Yang Zhao, Fan Liu, Hani Choudhry, Paul A. Khavari, Howard Y. Chang
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/ce192c166d4848879fbe0c187c228701
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!