ASK1 signalling regulates brown and beige adipocyte function

The protein kinase ASK1 has been linked to cellular stress responses. Here the authors show that ASK1 also regulates gene expression and activity of beige and brown adipocytes, and demonstrate adipocyte ASK1 has a physiological role in regulating thermogenesis in mice.

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Auteurs principaux: Kazuki Hattori, Isao Naguro, Kohki Okabe, Takashi Funatsu, Shotaro Furutani, Kohsuke Takeda, Hidenori Ichijo
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/ce51b10276424997a93a5ef2e239f66a
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