ASK1 signalling regulates brown and beige adipocyte function

ASK1 signalling regulates brown and beige adipocyte function

The protein kinase ASK1 has been linked to cellular stress responses. Here the authors show that ASK1 also regulates gene expression and activity of beige and brown adipocytes, and demonstrate adipocyte ASK1 has a physiological role in regulating thermogenesis in mice.

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Autores principales: Kazuki Hattori, Isao Naguro, Kohki Okabe, Takashi Funatsu, Shotaro Furutani, Kohsuke Takeda, Hidenori Ichijo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Q
Acceso en línea:https://doaj.org/article/ce51b10276424997a93a5ef2e239f66a
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spelling oai:doaj.org-article:ce51b10276424997a93a5ef2e239f66a2021-12-02T14:40:12ZASK1 signalling regulates brown and beige adipocyte function10.1038/ncomms111582041-1723https://doaj.org/article/ce51b10276424997a93a5ef2e239f66a2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11158https://doaj.org/toc/2041-1723The protein kinase ASK1 has been linked to cellular stress responses. Here the authors show that ASK1 also regulates gene expression and activity of beige and brown adipocytes, and demonstrate adipocyte ASK1 has a physiological role in regulating thermogenesis in mice.Kazuki HattoriIsao NaguroKohki OkabeTakashi FunatsuShotaro FurutaniKohsuke TakedaHidenori IchijoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kazuki Hattori
Isao Naguro
Kohki Okabe
Takashi Funatsu
Shotaro Furutani
Kohsuke Takeda
Hidenori Ichijo
ASK1 signalling regulates brown and beige adipocyte function
description The protein kinase ASK1 has been linked to cellular stress responses. Here the authors show that ASK1 also regulates gene expression and activity of beige and brown adipocytes, and demonstrate adipocyte ASK1 has a physiological role in regulating thermogenesis in mice.
format article
author Kazuki Hattori
Isao Naguro
Kohki Okabe
Takashi Funatsu
Shotaro Furutani
Kohsuke Takeda
Hidenori Ichijo
author_facet Kazuki Hattori
Isao Naguro
Kohki Okabe
Takashi Funatsu
Shotaro Furutani
Kohsuke Takeda
Hidenori Ichijo
author_sort Kazuki Hattori
title ASK1 signalling regulates brown and beige adipocyte function
title_short ASK1 signalling regulates brown and beige adipocyte function
title_full ASK1 signalling regulates brown and beige adipocyte function
title_fullStr ASK1 signalling regulates brown and beige adipocyte function
title_full_unstemmed ASK1 signalling regulates brown and beige adipocyte function
title_sort ask1 signalling regulates brown and beige adipocyte function
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/ce51b10276424997a93a5ef2e239f66a
work_keys_str_mv AT kazukihattori ask1signallingregulatesbrownandbeigeadipocytefunction
AT isaonaguro ask1signallingregulatesbrownandbeigeadipocytefunction
AT kohkiokabe ask1signallingregulatesbrownandbeigeadipocytefunction
AT takashifunatsu ask1signallingregulatesbrownandbeigeadipocytefunction
AT shotarofurutani ask1signallingregulatesbrownandbeigeadipocytefunction
AT kohsuketakeda ask1signallingregulatesbrownandbeigeadipocytefunction
AT hidenoriichijo ask1signallingregulatesbrownandbeigeadipocytefunction
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