The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ven...

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Auteurs principaux: Hikaru Eto, Yusuke Kishi, Nayuta Yakushiji-Kaminatsui, Hiroki Sugishita, Shun Utsunomiya, Haruhiko Koseki, Yukiko Gotoh
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/ce804acfbc32428c8f42eaeed912e0a0
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