MAVS-mediated apoptosis and its inhibition by viral proteins.
<h4>Background</h4>Host responses to viral infection include both immune activation and programmed cell death. The mitochondrial antiviral signaling adaptor, MAVS (IPS-1, VISA or Cardif) is critical for host defenses to viral infection by inducing type-1 interferons (IFN-I), however its...
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Main Authors: | Yu Lei, Chris B Moore, Rachael M Liesman, Brian P O'Connor, Daniel T Bergstralh, Zhijian J Chen, Raymond J Pickles, Jenny P-Y Ting |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
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Online Access: | https://doaj.org/article/ce9e45cacebe4770ab2eeb40d5b1b34b |
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