USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components

The ubiquitin-proteasome system regulates cellular reprogramming by degradation of key pluripotency factors. Here the authors report that the post-translational regulation of PRC1 components CBX4 and CBX6 by ubiquitination influences reprogramming.

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Bibliographic Details
Main Authors: Bo Ning, Wei Zhao, Chen Qian, Pinghua Liu, Qingtian Li, Wenyuan Li, Rong-Fu Wang
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/ce9e8507933b4b4c9760b0e18633d82d
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