HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP

The genome-wide investigation of chromatin organization enables insights into global gene expression control. Here, the authors present a computationally efficient method for the analysis of chromatin organization data and use it to recover principles of 3D organization across conditions.

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Auteurs principaux: Merve Sahin, Wilfred Wong, Yingqian Zhan, Kinsey Van Deynze, Richard Koche, Christina S. Leslie
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/cea56403ca294a09940716ef0bd1c22b
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