Intramolecular cohesion of coils mediated by phenylalanine--glycine motifs in the natively unfolded domain of a nucleoporin.

The nuclear pore complex (NPC) provides the sole aqueous conduit for macromolecular exchange between the nucleus and the cytoplasm of cells. Its diffusion conduit contains a size-selective gate formed by a family of NPC proteins that feature large, natively unfolded domains with phenylalanine-glycin...

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Bibliographic Details
Main Authors: V V Krishnan, Edmond Y Lau, Justin Yamada, Daniel P Denning, Samir S Patel, Michael E Colvin, Michael F Rexach
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
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Online Access:https://doaj.org/article/ceb5cd69ae3b4926bf29d2d110d8e741
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