GABAA Receptor Subunit Composition Drives Its Sensitivity to the Insecticide Fipronil
Fipronil (FPN) is a worldwide-used neurotoxic insecticide, targeting, and blocking GABAA receptors (GABAARs). Beyond its efficiency on insect GABAARs, FPN causes neurotoxic effects in humans and mammals. Here, we investigated the mode of action of FPN on mammalian α6-containing GABAARs to understand...
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Main Authors: | , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Subjects: | |
Online Access: | https://doaj.org/article/ceb9ff75ecb04493bc3f8dee993d1132 |
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