Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity
ABSTRACT Many viruses alter intracellular calcium homeostasis. The rotavirus nonstructural protein 4 (NSP4), an endoplasmic reticulum (ER) transmembrane glycoprotein, increases intracellular levels of cytoplasmic Ca2+ ([Ca2+]cyto) through a phospholipase C-independent pathway, which is required for...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2010
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/cebda0418e3644eb916811af7e0bb554 |
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