Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity

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Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity

ABSTRACT Many viruses alter intracellular calcium homeostasis. The rotavirus nonstructural protein 4 (NSP4), an endoplasmic reticulum (ER) transmembrane glycoprotein, increases intracellular levels of cytoplasmic Ca2+ ([Ca2+]cyto) through a phospholipase C-independent pathway, which is required for...

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Detalles Bibliográficos
Autores principales:	Joseph M. Hyser, Matthew R. Collinson-Pautz, Budi Utama, Mary K. Estes
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2010
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/cebda0418e3644eb916811af7e0bb554
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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