Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection

The conversion of auditory and vestibular stimuli into electrical signals is initiated by force transmitted to a mechanotransduction channel through the tip link. Here authors show that a single tip-link bond is more mechanically stable relative to classic cadherins, and that the double stranded tip...

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Bibliographic Details
Main Authors: Eric M. Mulhall, Andrew Ward, Darren Yang, Mounir A. Koussa, David P. Corey, Wesley P. Wong
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/cedc8ced7e7c4b7984736d122c8d046c
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