Late Na<sup>+</sup> Current Is [Ca<sup>2+</sup>]<sub>i</sub>-Dependent in Canine Ventricular Myocytes

Late Na<sup>+</sup> Current Is [Ca<sup>2+</sup>]<sub>i</sub>-Dependent in Canine Ventricular Myocytes

Enhancement of the late sodium current (I<sub>NaL</sub>) increases arrhythmia propensity in the heart, whereas suppression of the current is antiarrhythmic. In the present study, we investigated I<sub>NaL</sub> in canine ventricular cardiomyocytes under action potential volta...

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Autores principales: Dénes Kiss, Balázs Horváth, Tamás Hézső, Csaba Dienes, Zsigmond Kovács, Leila Topal, Norbert Szentandrássy, János Almássy, János Prorok, László Virág, Tamás Bányász, András Varró, Péter P. Nánási, János Magyar
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
late Na<sup>+</sup> current
cytosolic Ca<sup>2+</sup> concentration
CaMKII
action potential voltage clamp
canine myocytes
Medicine
R
Pharmacy and materia medica
RS1-441
Acceso en línea:https://doaj.org/article/cedd9842b323421d81788f7c883d48be
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https://doaj.org/article/cedd9842b323421d81788f7c883d48be

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