The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope

The TERB1-TERB2-MAJIN complex mediates the attachment of telomeres to the nuclear envelope. Here the authors present the crystal structures of the human TERB1-TERB2 and TERB2-MAJIN subcomplexes and show that Terb2 mutations, which abolish complex formation cause aberrant homologous pairing and disor...

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Autores principales: Yan Wang, Yanyan Chen, Juan Chen, Lijun Wang, Leitong Nie, Juanjuan Long, Haishuang Chang, Jian Wu, Chenhui Huang, Ming Lei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ceff7286fa6646f191c18e473d4322e4
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