IKKε isoform switching governs the immune response against EV71 infection

Chang et al. show that Enterovirus 71 (EV71) infection upregulates IKKε isoform 2 (IKKε v2), which in turn activates interferon regulatory factor 7 (IRF7). This study suggests that host cells trigger IKKε isoform switching to increase the production of interferon against EV71 infection, providing a...

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Autores principales: Ya-Ling Chang, Yu-Wen Liao, Min-Hsuan Chen, Sui-Yuan Chang, Yao-Ting Huang, Bing-Ching Ho, Sung-Liang Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cf0a06bd1056452785cc2fdda4a477a3
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