Induced fit versus conformational selection: From rate constants to fluxes… and back to rate constants

Abstract Induced fit‐ (IF) and conformational selection (CS) binding mechanisms have long been regarded to be mutually exclusive. Yet, they are now increasingly considered to produce the final ligand‐target complex alongside within a thermodynamic cycle. This viewpoint benefited from the introductio...

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Autores principales: Georges Vauquelin, Dominique Maes
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/cf1070c49534475f88ff1335da182eab
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